- Artesunate 100mg, Sulphadoxine 500mg and Pyrimethamine 25mg Tablets
Artesunate is prodrug which converted into active form as a dihydroartemisinin (DHA) which act as a strong schizontisides, active against ring stage of parasite
Sulphadoxine competitively inhibits dihydrofolic acid in malarial parasites.
Pyrimethamine competitively inhibit the enzyme dihydrofolate reductase in malarial parasites.
Artesunate, Sulphadoxine and Pyrimethamine Tablets prescribed in following condition:
- Acute, uncomplicated P. falciparum malaria for those patients in whom chloroquine resistance is suspected
- First-line therapy for management of uncomplicated Plasmodium falciparum malaria
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