- Voglibose 0.3mg and Metformin 500mg Tablets
Voglibose is an α-glucosidase inhibitor, which slows the absorption of carbohydrates due to competitive inhibition of α-glycosidase in the small intestine as a result it decrease post meal plasma glucose levels, that leads to decreased diurnal insulin secretion.
While on the other hand metformin reduces gluconeogenesis in the liver by activating AMP-activated protein kinase (AMPK) along with that it increases glucose utilization and insulin sensitivity. Consequently, it lowers plasma glucose level, in the fasting condition additionally, it reduces triglycerides and low-density lipoprotein (LDL)-cholesterol, which is helpful in maintaining a favorable cholesterol profile in patients.
Voglibose & Metformin Tablets prescribed to patients in below mentioned conditions under prescriber’s observation:
- In the treatment of type 2 diabetes
- When dietary changes, exercise, and weight loss alone not enough to control glycemic index in patients
PRECAUTIONS:
Because this medicine has the potential to cause hypoglycemia or hypoglycemic symptoms, it is crucial to choose the right patient, administer the medication correctly, and follow all dose and administration recommendations. When caloric intake is inadequate, when vigorous activity is not offset by caloric supplements, or when other glucose-lowering medications or ethanol are used concurrently, there is an increased risk of hypoglycemia.
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